Genes behind deadly heart condition found, scientists say


Scientists found genes that cause a heart disease that kills 50% of victims within five years.


Scientists looked at the genes of people with pulmonary arterial hypertension to find out what was causing the condition


Scientists say they have identified genes that cause a deadly heart condition that can only be cured by transplants of the heart or lungs.

Pulmonary arterial hypertension kills 50% of those affected within five years, but little was known about what caused the condition in some people.

The research says they have discovered five genes that cause the illness.

The findings could lead to earlier detection of the disease and ultimately new treatments, researchers say.

Pulmonary arterial hypertension (PAH) affects around 6,500 people in the UK and cause the arteries to stiffen and thicken and leading to the heart disease. It is often diagnosed in people who have other heart or lungs conditions and it can affect people of any age, research says.

Scientists said, to cure this disease is to transplant of the heart and particularly the lungs, but the body will reject them due to the waiting list for organ transplants, particularly in the case of lungs.

They found that mutations in five genes were responsible for causing the illness in these people, including in four genes that were not previously known to be involved in the disease.

In people with the condition these genes fail to effectively produce the proteins that are required for the structure, function, and regulation of the body’s tissues, researchers found…………. READ MORE.………



Author: Wan